Edge of Growth and Maduration

31 março 2017, Comments 0

Edge of Growth and Maduration


Does the Timing of Puberty Matter?

A live Conversation between Ze’ev Hochberg and Jean-Pierre Bourguignon, moderated by Alan Rogol, with contributions: Cheri Deal, Michael RankeJan-Maarten Wit, Ron Rosenfeld, Alicia BelgoroskyIvo Arnhold,  David Dunger, Martin Ritzen, Leo Dunkel, Raphael Rappaport, Paul Czernichow

Ze’ev Hochberg: I like to think of adolescence, a broader perspective: it is a life history stage when children prepare for adult roles, in terms of reproduction, independence and caring for a family. So, eventually, at the end of puberty, they will have to become adults. When I think of adolescence, I think of a package that includes puberty and its related neuroendocrine changes, the secondary characteristics of puberty, the growth spurt, the cognitive changes that occur in puberty, and the psychological development that is occurring in puberty, including the acquisition of sexual and reproductive skills. So that in the center is how to become a reproductively competent adult, the so-called ‘coming of age’. 

The full Conversation is on:



What discovery impressed you most during your career?

A live Conversation between Ron Rosenfeld and Cheri Deal, with contributions by Ze’ev HochbergAlan RogolJan-Maarten WitAlicia Belgorosky, Paul Czernichow. David Dunger, Ralph Rappaport, Leo Dunkel, Martin Ritzen

Cheri Deal: I have the pleasure of being able to probe Ron Rosenfeld’s brain. The question posed to Ron is “What scientific discovery did you feel, in your career, has made the most impact”. So, go ahead and give us your answer.

Ron Rosenfeld: Thank you Cheri. All of us in our investigative careers have had the experience of coming across a paper or a lecture where you said, “Wow, this has just opened up a whole new area of thinking.” And for me there’s no question that the paper (series of papers) that most impacted me were Argiris Efstratiadis knock-out models, which I think opened the entire growth hormone IGF system (Nature. 1990;345:78-80,  Cell. 1991;64:849-59) …

The full Conversation is on:



Bar Mitzvah and puberty during ancient times

Diana Sperling, PhD. Philosopher, writer, essayist, teacher, the National University Cordoba, Argentina

Alicia Belgorosky, MD, PhD, Chairwoman of Endocrine Department, Hospital de Pediatría Garrahan, Buenos Aires, Argentina

With contributions by Ivo ArnholdJean-Pierre BourguignonZe’ev HochbergJan-Maarten WitMark SperlingAlan RogolMichael Ranke

Alicia Belgorosky: What was the criterion to establish the age to become a Bar Mitzvah at 13 years?

Diana Sperling: The criterion to establish that age was related to the age at puberty, that is, the age at onset of sexuality and the physical ability of reproduction. Of course, the criteria we currently analyze – from a scientific point of view or in psychoanalysis, etc –, were not necessarily conscious reasons in those times. For example, in the Jewish religion, hand washing has been mandatory before meals, prayer, and at many other moments in daily life. Only many centuries later, scientists discovered the usefulness of this ritual. In other words, in all ancient cultures or “religions”, certain knowledge about actual life was imposed and then “explained” as being commanded by God.

The full Conversation is on:


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